If used for prostate cancer treatment, one shot per month, generally refers to the Norelide shot. The Norelide shot is indicated as a drug for endocrine treatment of prostate cancer. Norelide is an extended-release implant of goserelin acetate, which plays the role of a drug depot. Prostate cancer is an androgen-dependent tumor. For some patients with mid to late stage prostate cancer, if they have lost the opportunity to have radical prostate cancer surgery or if the patient’s physical condition is poor and cannot tolerate radical prostate cancer surgery, they can choose to have endocrine therapy. This is to block the formation of androgens in the body, which can be done in two main ways, one is surgical removal of both testicles, and the other is through the injection of Norelide injections to achieve the effect of drug depot. Due to the surgical removal of testicles, for patients with a relatively large psychological burden, now more and more patients will choose to achieve the effect of de-escalation by means of drug de-escalation. Usually in the use of norelide injection on the basis of, and then add oral anti-androgen drugs, more commonly used drugs is bicalutamide, so that through the norelide injection plus oral anti-androgen drugs, can achieve the maximum effect of androgen blockade.