Clomiphene primarily works to promote ovulation in women, and the primary mode of action of Clomiphene is through competitive binding to effective estrogen receptor sites in the hypothalamus. Estrogen is displaced from these sites, and the hypothalamus perceives a marked lack of circulating estrogen, which leads to gonadotropin-releasing hormone stimulation of follicle-stimulating hormone and luteinizing hormone, which may trigger a normal menstrual cycle, thus acting as a definite ovulation promoter. It is suitable for use in patients with polycystic ovary syndrome, and is also suitable for use in patients undergoing assisted conception techniques, such as in vitro fertilization, and this medication should always be used in accordance with a specialist’s instructions. In conclusion, Clomiphene mainly has the effect of promoting ovulation.