In order to make their babies healthy and not lose at the starting line of life, more and more couples pay attention to preconception care. Pre-conception care is usually carried out four to six months before conception is planned. The purpose of preconception health care is to prevent congenital or hereditary diseases from occurring in the offspring, to avoid damage to the reproductive cells and their functions caused by harmful factors in the environment, and also to enable the mother-to-be to conceive and raise the next generation in the healthiest state. The contents of preconception health care include: (1) Knowing the medical history: including the time of marriage, sexual life after marriage, contraceptive status and previous reproductive history. For those who have had miscarriage, stillbirth, stillbirth or unexplained neonatal death or delivered a child with birth defects and other adverse maternal history, it is even more necessary to cooperate with the doctor to further understand the relevant medical history, including infections, medication, complications and genetic factors. (2) Physical examination: including general examination and gynecological examination. Suggested items for mandatory pre-pregnancy checkup: ①Blood test (blood type): early detection of anemia and other blood system diseases. If the mother is anemic, not only will there be complications such as postpartum hemorrhage and puerperal infections, but it will also affect the baby in the future, which will bring a series of impacts to the baby. For example, easy to infection, decreased resistance, growth and development backward. ② Urine routine: helps in the early diagnosis of kidney disease. Ten months of pregnancy is a huge test for the mother’s renal system, the body’s metabolism increases, which will increase the burden on the kidneys. If there is a kidney disease, the condition will be heavier after pregnancy. ③Fecal routine: It helps to diagnose digestive system diseases and parasitic infections, such as Toxoplasma gondii infection, which, if not detected early, can lead to serious consequences such as miscarriage and fetal malformation. ④ Liver function (two-to-five): diagnosis of various types of hepatitis and liver damage. If the mother is a patient with viral hepatitis and it is not detected in time, pregnancy can cause very serious consequences, such as preterm labor and neonatal death. Hepatitis virus can also be transmitted vertically to the child. ⑤ Chest X-ray: It helps in the diagnosis of tuberculosis and other lung diseases. When a woman with tuberculosis becomes pregnant, the use of medicines will be restricted, which will affect the treatment. Moreover, active tuberculosis will often be aggravated by postnatal exertion, and there is a risk of transmission to the child. (6) Gynecological endocrine complete set: diagnosis of ovarian diseases such as menstrual irregularities. (7) Leukorrhea routine: screening for trichomonas, mold, and bacterial infections. If you have a sexually transmitted disease, it is best to treat it first and then get pregnant. Otherwise, it is easy to cause miscarriage, premature labor, premature rupture of membranes and other dangers. Chromosome test: early detection of genetic diseases such as Crohn’s disease, infertility and Turner’s syndrome. Other related tests, such as kidney function, blood sugar, sexually transmitted diseases (AIDS, syphilis, etc.), liquid-based cytology, special pathogens (rubella virus, toxoplasmosis, etc.). Pre-conception health care should start from the following aspects: (1) Both husband and wife are in good physical and psychological condition to ensure the provision of high-quality sperm and eggs. (2) Good genetic or disease counseling. Those who have a family history of genetic or hereditary diseases, suffer from other diseases or are taking certain medications should be counseled before conception. Choose the time of conception or switch medications, etc. under the guidance of a doctor to avoid adverse effects on the fetus. (3) Avoid conception under fatigue or poor mood. (4) Reasonable nutrition, correcting partiality of food, and abstaining from smoking and alcohol. (5) Stay away from heavily polluted work or living environments. (6) Record the menstrual cycle, recognize and master the ovulation period. (7) Couples using intrauterine devices or oral contraceptive pills for contraception should plan for conception after consulting with a doctor after removing the devices or stopping the pills. (8) Prevent various infectious diseases, especially rubella and shingles. (9) Keep away from pets to prevent toxoplasmosis infection. Vaccination can be given six months before conception. (10 Start taking folic acid 3 months before planned conception to help prevent fetal neural tube malformation.