The platelet count (PLT) is the product of the mean platelet volume (MPV) and the platelet count (PLT), which is related to the number and size of platelets. The causes of high platelet volume include physiological and pathological. 1. Physiological causes: The blood of pregnant women in late pregnancy is in a state of hypercoagulation, and thus may have a high platelet volume. It can also be temporarily high after strenuous exercise and meals, and can recover after rest. In addition, platelet count varies by season and time of day. It is higher in winter than in spring, and the value is higher at noon than in the morning. In women, there are also slight fluctuations around the menstrual period. 2. Pathological causes: For example, patients with myelofibrosis may have abnormalities such as high platelet ratio and decreased hemoglobin; patients with splenectomy may have high platelet ratio, white blood cells and red blood cells. Because the spleen is the site where platelet destruction occurs, rebound may occur after removal of the spleen; patients with chronic granulocytic leukemia may have high platelet count, leukocytosis, and decreased red blood cells. If the platelet ratio is only high, it does not confirm the diagnosis of the disease. It is necessary to improve the relevant tests such as coagulation tetralogy and biochemical combination under the guidance of a doctor to clarify the cause of the disease and then give the right treatment for the cause. When it causes symptoms such as vomiting and diarrhea, fluid should be actively rehydrated. When infection occurs, antibiotics should be used for treatment. If it is caused by primary thrombocytosis, it may be necessary to use a machine to separate the platelets to solve the problem at the root.