When hepatitis B virus core antibody is positive, hepatitis B virus E antibody is positive, and the remaining three of the hepatitis B penta tests are negative, it means that the hepatitis B virus has been infected in the past and has recovered, or in combination with hepatitis B surface antigen positivity, it is a minor triple positive. Positive core antibody to hepatitis B virus indicates previous or recent infection with the virus, while positive E antibody to hepatitis B virus usually indicates relative improvement of hepatitis B. Positive E antibody to hepatitis B virus indicates that the replication of the hepatitis B virus has changed from active to quiescent, and the contagiousness of hepatitis B virus has become relatively low at this time. Therefore, when both of them are positive and the other three are negative, it means that the human body is infected with hepatitis B virus, but after treatment, it has improved or has been cured by itself, if combined with hepatitis B surface antigen positive, it means that the patient is hepatitis B minor triple Yang. Regardless of whether the hepatitis B e antibody and hepatitis B core antibody are positive or not, it is recommended to further check the hepatitis B penta, hepatitis B virus DNA quantitative and other related tests to clarify whether it is still infectious and then carry out the treatment, and if necessary, also need to check the liver function and so on.