Many young men with hepatitis B often worry about fertility issues, while thinking about curing hepatitis B first to avoid infecting children later, while thinking about whether it is too late to have children after curing hepatitis B. At the same time, they also have to worry about whether the anti-viral drugs used now will be bad for future children, or in case they accidentally have children during treatment, in a word, “recently In a word, “I’ve been having a lot of trouble lately”. In fact, young men with hepatitis B should plan their fertility before antiviral treatment. For those who do not have any plans to have children in the near future, they can first consider antiviral treatment and then stop taking the medication after they have obtained satisfactory treatment results before considering having children. If there is no contraindication, antiviral drugs can be preferred to interferon, because its course is relatively short, and it is not easy to relapse after successful treatment, so it is beneficial for patients to finish treatment and start conception as soon as possible, but only 6 months after stopping the medication can be considered for conception. If there is an urgent need for fertility in the near future and it is not possible to accept antiviral treatment first, we can consider conception first and antiviral treatment later. This option may theoretically lead to vertical transmission of hepatitis B virus from father to child through infected sperm, but the probability is very low. Patients receiving interferon antiviral therapy who wish to conceive in the near future should stop taking the drug for 6 months before having a child, and should not have a child during the treatment period; in case of unintended conception, the woman is generally advised to terminate the pregnancy with full knowledge of the associated risks. In the case of unintended conception, the woman is generally advised to terminate the pregnancy if the risks involved are fully understood. If a patient receiving nucleoside analogue antiviral therapy intends to have a child in the near future, she may consider having a child during the treatment period if the risks and benefits associated with the drug are fully understood and the pros and cons are weighed.