Blood creatinine 114 μmoI/L is stage 2 nephropathy, a compensatory stage of renal insufficiency, glomerular filtration rate should be 60-89 mL/min, clinical symptoms are not obvious, can be manifested as symptoms of the primary disease, such as chronic glomerulonephritis with abnormal urinalysis, proteinuria, hematuria, tubuluria, satisfactory blood pressure control, may have edema, patients with diabetic nephropathy appear dominant proteinuria and hypertension. Patients with hypertensive nephropathy have also developed abnormal urinalysis and moderate hypertension, etc. It is vital for patients with stage 2 kidney disease to do a good job of kidney protection, a diet low in salt, high quality low protein, low fat, ensure the supply of calories, avoid infection, exertion and renal ischemia conditions in life, quit smoking and alcohol, and strengthen physical exercise to improve resistance. Strictly follow the medical advice to use drugs and prohibit the use of nephrotoxic drugs to delay the time to enter stage 3.