Cefixime and Azithromycin are not recommended to be taken together. Cefixime is a cephalosporin antibiotic, Cefixime contains a beta-lactam ring semi-synthetic antibiotic. It mainly acts on the bacterial cell wall and is a bactericide. Azithromycin belongs to the macrolide class of antibiotics, aminoglycoside antibiotics, whose main function is to interfere with the synthesis of cellular proteins. The two are not recommended to take together because cefixime is a rapid bactericidal agent, azithromycin is a rapid bacteriostatic agent, taking at the same time has an antagonistic effect. And taking azithromycin to inhibit bacterial reproduction at the same time, and then using a rapid bactericidal agent, will also affect the effect of the drug. So cefixime azithromycin can not be taken together. It is recommended that when using drugs to treat diseases, the cause of the disease should be identified and used under the guidance of a physician. In order to avoid the improper use of uncomfortable symptoms, not conducive to health.