First, the clinical manifestations of mania: The main clinical symptoms of manic state are high state of mind, thinking and psychomotor excitement. 1, high state of mind The patient is relaxed, happy, giddy, complacent, joyful attitude, as if there is no trouble on earth. The elevated state of mind is often vivid, vivid, in harmony with the inner experience and the surrounding environment, and is infectious. Patients often describe themselves as “happy-go-lucky”, “overjoyed”, and “full of sunshine and splendor in life”. Emotional reactions may be unstable and irritable, and they may be irritated by small trivial matters or opinions being refuted or demands not being met, and they may show destructive or aggressive behaviors, but later they may behave as if nothing is wrong and relaxed. Some patients can also appear briefly in a bad mood during the manic period. 2.Thinking is running. The process of association is obviously accelerated, concepts come one after another, and there is a lot of talking and incessant. Because of the distraction, the topic often shifts with the situation, and the concept may appear to drift and the phenomenon of phonetic association. Patients often have the experience of “brain enlightenment”, “getting smarter”, “tongue racing with thoughts”. 3.Excessive self-evaluation On the background of high state of mind, the patient feels good about himself. Feeling healthier and more energetic than ever before. A quick mind and a quick eye. Often over-evaluate their own talent, status, pretentiousness, may appear exaggerated concept. 4.Psychomotor excitement The manic patient has a wide range of interests, likes to be lively, has many interactions, and takes the initiative to get close to people, and even meets people he does not know at once. Busy and busy, do not know fatigue. Amusing with others, nosy, and fighting for justice. The patient often talks a lot, quotes scriptures, speaks incessantly, giving people the impression that he or she is talking out of his or her mouth, and lacks thoughtfulness in everything, and often has a head but not a tail, and lacks effectiveness; sometimes he or she shows that he or she spends extravagantly, shopping and making phone calls beyond his or her financial capacity. Although the patient talks a lot, moves a lot, and is even hoarse, he is not tired, and his energy seems abnormal. 5, physical symptoms Manic patients rarely have physical discomfort because they feel good about themselves, but after careful observation, we can still find that the patient often has a rosy face, eyes, and symptoms of sympathetic excitement such as accelerated heart rate and constipation; due to excessive physical exertion, there is more weight loss; sometimes there is an increased appetite and libido, which is manifested as frivolous behavior and good proximity to the opposite sex. In addition, because of the reduced need for sleep, often to late at night do not want to sleep, do not know tired, directly affect the normal rest of the surrounding people, which will also lead to the deterioration of the relationship with the surrounding people. It is rare to see single-episode mania clinically, and the cases with only manic recurrent episodes are even rarer, therefore, we usually see more clinical features of alternating episodes of mania and depression, which is called bipolar affective disorder or called manic-depressive disorder. In short, mania belongs to a kind of affective mental disorder, once the above-mentioned typical clinical manifestations are found, professional intervention should be requested immediately to achieve early detection and early treatment, and the treatment for mania should generally be based on regular medication. In addition, the disease is prone to relapse, in the prevention of relapse, the simultaneous application of medication and psychotherapy can help to improve the efficacy, at the same time, the necessary family and social support system also has a very positive role in preventing the relapse of the disease, such as solving the practical difficulties in study, work and life as much as possible, creating a relaxed and pleasant environment for the patient as much as possible, and relieving or reducing the excessive psychological burden or pressure. Second, the course of the disease and prognosis Whether it is a single manic episode or recurrent mania, most of them are acute or subacute onset, and the good season is late spring and early summer. The age of onset of mania is around 30 years old, of course, there are also early onset, in the 5-6 years old onset, there are also late onset, after 50 years old, but more than 90% of the cases start before 50 years old. The natural course of mania is generally considered to last from a few weeks to 6 months, with an average of about 3 months, and some cases last only a few days, and individual cases can last more than 10 years. Some people believe that recurrent mania, each episode lasts almost similarly, and can become chronic after many episodes, and a few patients have residual mild affective symptoms, and social function is not fully restored to the pre-morbid level. Modern treatment can eventually lead to complete recovery of 50% of patients. It has been suggested that only one episode in a lifetime accounts for only 5% of cases, but others believe it can be as high as 50%. During the first 3 episodes, the interval between each episode becomes shorter and shorter, and the duration of the interval between subsequent episodes does not change. For each episode, the rate of significant and complete remission is 70% to 80%.