The patient always wakes up in the middle of the night belongs to the sleep disorder, neurological weakness, the main reasons to consider the following: 1, with the patient’s psychological factors have a relationship, such as patients nervous, anxiety is easy to always wake up in the middle of the night, and it is difficult to fall back to sleep after waking up. 2, may be related to the patient’s bad habits, such as the patient wakes up in the middle of the night to look at the phone, play games, do things that have nothing to do with sleep, long-term will lead to patients appear biological clock disorder. 3, the patient in the middle of the night always wake up may also be caused by frequent urination and other reasons.