The skin lesions may be keratotic protuberance symptom is one of the main symptoms of actinic keratosis, which is caused by occlusion of keratinized pores by keratocysts in the form of pore-like keratinized papules of unknown etiology. Some patients have hypothyroidism. In some patients, the condition occurs as a result of corticosteroid injections or administration. It is common in patients with atopic tendencies or is hereditary, occurring in the same family. The following symptoms of the disease can be used for self-examination. 1. Typical skin lesions with a paste-like appearance in the favored areas; 2. Histopathology: hyperkeratosis and papillomatous hyperplasia, visible as keratocysts, with tumor cells composed of basaloid cells.