The amniotic membrane usually heals within a day after amniocentesis, with some patients requiring a longer recovery time. The amniotic membrane is a translucent membrane made up of a single layer of epithelial cells, which secretes amniotic fluid and is resilient. Amniocentesis uses a small needle eye and the doctor will apply gauze pressure after the puncture, which helps the wound to heal. However, when the puncture site is infected, this can affect the healing process and the patient’s healing time can be relatively longer. Therefore, amniocentesis must be performed in a regular hospital, where the obstetrician will follow aseptic operation throughout the procedure to avoid surgical infection. In addition, after the operation, pregnant women should pay attention to protecting the needle eye cleanliness, bed rest, avoiding needle eye contamination, walking for a long time, prohibiting excessive exertion, sexual life, and strengthening nutrition to promote wound healing.