Amniocentesis, also known as amniocentesis. It is usually performed between 14 and 20 weeks of pregnancy and is performed by passing a thin needle through the pregnant woman’s belly under the guidance of ultrasound, reversing the uterine wall, entering the amniotic fluid cavity and extracting amniotic fluid for a comprehensive examination. If the couple has no family history of hereditary diseases, the mother-to-be has no previous history of adverse pregnancies (spontaneous abortion, premature birth, malformed fetus, etc.), and the mother-to-be has concerns about amniocentesis, she can also undergo a three-dimensional ultrasound examination of the fetus at 20-26 weeks of pregnancy to minimize the birth of fetuses with congenital defects. Amniocentesis is one of the most accurate methods of screening for malformations, as Down’s syndrome screening has only a 70% accuracy rate. If the Down’s syndrome screening shows a high risk, it is still recommended that the mother-to-be have an amniocentesis test. During labor, the fetus is often in distress due to prolonged labor, lack of oxygen or compression. The sex of the fetus can be determined by the chromosomes in the amniotic fluid, and can be determined by the measurement of the endocrine secretions contained in the amniotic fluid. Operation: The doctor will confirm the location of the puncture by ultrasound, then apply alcohol to the mother’s abdomen, cover the abdomen with a perforated surgical cloth, and use a long needle about 15 cm long to penetrate the abdomen in this position. The needle will pass through the abdominal wall and the uterine wall in turn. Sensation: During the procedure, the abdomen may feel a little tight, or there may be a tingling or pressure sensation. Or you may not feel any discomfort. Amniocentesis is generally recommended for high-risk women aged 35 years or older. If you are under 35 years of age but are found to be at high risk after intravenous screening for Down’s syndrome, you should also have an amniocentesis as a safety precaution. Amniocentesis is mainly used for prenatal diagnosis at 18-23 weeks of gestation when medically indicated. The scope of diagnosis is chromosomal diseases, DNA mutation analysis, and inherited metabolic diseases. Medical indications: 1. The pregnant woman is older than or equal to 35 years old; 2. The pregnant woman has given birth to a child with chromosomal abnormalities; 3. One of the spouses has chromosomal abnormalities; 4. The pregnant woman has given birth to a child with monogenic disease or genetic metabolic disease; 5. High risk of serum biochemical screening (Down’s syndrome screening); 6. Fetal abnormalities found by ultrasonography. For example: early-onset amniotic fluid, especially with intrauterine growth restriction, short fetal limbs, abnormal thickening of fetal nuchal translucency or nuchal hydatid cyst, fetal hydronephrosis, renal malformation, hydrocephalus or enlarged lateral ventricles, choroid plexus cyst, posterior cranial fossa widening, single umbilical artery, umbilical cord cystic mass, umbilical bulge, congenital heart anomaly, multiple strong echogenic spots in the heart, strong intestinal echogenicity, short nasal bone, multiple malformations The following are some of the most common amniocentesis tests: cleft lip and palate with other anomalies, persistent hyperhydramnios, and unexplained fetal edema. Amniocentesis is done to screen for chromosomal abnormalities in order to reduce the number of dumb and stupid babies born. Therefore, pregnant mothers should have amniocentesis under the guidance of their doctors to have a healthy and cute baby!