Hepatitis B surface antibody 250mIU/ml means that the patient is positive for Hepatitis B surface antibody, there is no need to vaccinate against Hepatitis B, there is no risk of disease, this is a kind of protective antibody, which is beneficial to the body. Under normal circumstances, when the titer of hepatitis B surface antibody is above 10mIU/ml, it means that hepatitis B surface antibody is positive, and it has certain resistance to hepatitis B. The purpose of hepatitis B vaccination is to produce protective hepatitis B antibody to resist the attack of hepatitis B virus and prevent the occurrence of hepatitis B. It is recommended that patients should be tested every three years. It is recommended that patients should be tested every three years to determine the titer of Hepatitis B antibody, if the titer of Hepatitis B surface antibody is below 30mIU/ml, it is necessary to strengthen Hepatitis B vaccine; if the titer of Hepatitis B surface antibody is above 10mIU/ml but below 20mIU/ml, it is necessary to strengthen Hepatitis B vaccine with two injections. If you need to receive hepatitis B vaccine, please consult a regular hospital, and if you feel sick, consult a doctor in time.