Kidney diseases such as acute and chronic glomerulonephritis, renal insufficiency (including renal insufficiency and uremia) are common and frequent; and with the improvement of living standards and changes in diet structure, various secondary kidney diseases are gradually increasing, such as the incidence of diabetic nephropathy and hypertensive nephropathy is high. Although the level of medical care is improving, health conditions are improving, the efficacy of kidney disease has been greatly improved, but there are still many diseases that have no special effects or fundamental solutions, many kidney diseases are characterized by long-term (chronic), easy to recur, gradually aggravated, and some finally must rely on dialysis or kidney transplantation. Therefore, how to meet the needs of the majority of kidney patients, especially the difficult and critical kidney disease is particularly urgent, a variety of kidney disease medical institutions came into being. Most of the tertiary hospitals in China have opened nephrology specialties, and even nephrology institutes and key laboratories. And there are some kidney disease hospitals or outpatient clinics, or grassroots clinics hire some kidney disease experts from large hospitals to sit in the clinic, which are convenient for kidney disease patients to seek medical advice. As a few kidney disease through the hospital’s formal, systematic treatment, clinical failure to cure or only controlled, delayed the progress, then some patients subjectively always hope to be completely cured, completely cut off, especially in the treatment process can not be immediate results, patients are prone to take a fluke, to believe in a variety of false, exaggerated advertising, thinking to try, in case it is cured? Even if the cure is not good, it is not too late to go back to the big hospital. In addition, some advertisements can really move your heart, not to mention its advertising words are how attractive, and look at its release of advertising units will not let you believe. Generally are published in the provincial and municipal media, more than hundreds of thousands of yuan in the national television, newspapers and magazines for the introduction, publication advertising, and this authoritative media advertising really let you have to believe. We can say this, for the boast of “complete cure”, “quick effect, root”, “99% (100%) effective”, “invalid refund The “very vigilant, do not hold to try, bad even if more wasted money idea and treated hastily. It is not worthwhile to spend unjust money, the patient has spent a lot of money for the treatment of pain, and then spend unjust money, pay “tuition” is undoubtedly worse; worse is so a toss on the missed time for treatment, delay or aggravate the disease, and even cause irreversible damage, the rapid deterioration of kidney function, and even death. This is always encountered in clinical outpatient clinics and wards every year a few, more than a dozen. For example, Zhang XX, male, 40 years old, renal insufficiency (azotemia stage), after treatment, the blood creatinine stabilized at about 300μmol/L, and the patient’s conscious symptoms were not obvious. However, the patient did not believe that this was the way to live his life, and always wanted to be completely cured, so that the blood creatinine could be reduced to normal. So he saw an advertisement in the newspaper introducing a medical treatment for the disease in a certain place, and spent more than 5,000 yuan, and came back in less than 2 months, and when we met again, he was almost unrecognizable and changed too much: the patient’s whole body was highly swollen, he had panic and shortness of breath, severe anemia, nausea and vomiting, and his urine output was extremely low. After 40 days of treatment with a combination of Chinese and Western medicine, the patient finally turned to safety. This patient was lucky. The other patient, Li, was not so lucky. Although his condition was almost identical, the results were very different. Because of the obsession, he went around to doctors, and finally had to undergo dialysis treatment, and has been on dialysis for more than 2 years, while the patient in front of him still insists on taking Chinese medicine treatment in the outpatient clinic, and his blood creatinine is stable between 350~420μmol/L, and he can participate in light work. At present, the two most difficult bones in the kidney disease field are refractory nephrotic syndrome and chronic renal failure. There are no particularly effective means both nationally and internationally. Most of the former will take the road to renal failure, while the latter is prone to develop to the point of uremia. Is uremia an incurable disease? The answer is no. After decades of efforts, China’s unique combination of Chinese and Western medicine treatment, hemodialysis (commonly known as blood washing), peritoneal dialysis (commonly known as belly washing), kidney transplantation (commonly known as waist replacement) technology has been perfected, the longest survival of dialysis and transplantation patients have been more than 30 years, and now with the early dialysis of uremia, patients can get a normal life expectancy. And the gradual development of medical insurance, the coverage continues to expand, for the majority of dialysis patients who can hardly afford the high cost can be expected to fundamentally improve the difficult dilemma of finally giving up treatment because of lack of money. Refractory nephrotic syndrome, as the name implies, is indeed difficult to treat, and quite a few cases may still be ineffective despite regular, systematic treatment, at which point the goal of treatment should be shifted to protecting kidney function, rather than futilely trying to reduce urine protein. It is also at this time, when the regular hospitals feel helpless, patients are most likely to believe in advertising boasts and blindly seek medical help, which often results in rapid deterioration of kidney function, making people distressed. For patients with kidney disease, how to properly seek medical help? Here we make a few suggestions. One is to attend regular medical checkups, which is the main means of early detection of kidney disease; in addition, we should actively seek medical help if we feel abnormal. For example, if you suddenly have swollen eyelids, face or ankles, go to the hospital and have your urine checked to rule out nephritis. Another point, which is very important, is that if you find that your blood pressure is elevated, you must check your urine for protein in order to rule out renal hypertension. Because many hypertension is secondary to kidney disease, if the primary cause of kidney disease is not treated promptly and correctly, hypertension cannot be effectively controlled and is delayed. Others, such as nausea and vomiting, anemia, unrelieved fatigue, bone pain, persistent itchy skin, etc., should be considered for the possibility of kidney failure and uremia, especially after a stage of seeing other departments without effect. Secondly, the kidney disease should not go around to random doctors, but should go to a regular large hospital nephrology specialist, where the emphasis on nephrology specialist, rather than the general general internal medicine. We strongly oppose to find the wandering doctor on the telephone pole, the special medical institutions that “cure kidney disease” and the so-called “senior kidney disease experts” to treat. Oppose frequent changes of hospitals and doctors. Don’t shake your confidence and change doctors or hospitals because you can’t see the effect in one or two weeks or one or two months. Because most kidney diseases are slow to take effect, such as nephrotic syndrome, even hormone-sensitive types take 2-3 weeks to see its effect, and chronic renal failure, uremia is more unlikely to short-term blood creatinine has dropped as the only criterion for effective. Third, patients with kidney disease should understand their own condition, their own medication, and their own primary care physician, to firmly establish confidence in long-term treatment. Fourth, follow the doctor’s advice, do not buy drugs, change drugs, stop taking or miss taking, increase or decrease the dose. For special medications, such as taking prednisone, patients are required to take the medication during the prescribed time (usually between 6-8 am), which helps to reduce the suppression of adrenal cortical function by hormones. When patients with kidney disease see other diseases, tell the attending physician that they have kidney disease and those drugs cannot be applied. For example, some antibiotic drugs, antipyretic and analgesic drugs and some toxic and aristolochic acid-containing Chinese medicines cannot be taken freely because they are toxic to the kidneys.