Mycoplasma infection patients need to take the cyclic ester drug roxithromycin treatment, the specific treatment time is related to the severity of the disease, usually need more than 3 days. 1. mild infection: may cause high fever, cough sputum and sputum symptoms, men will cause penile redness and swelling and itching, women will cause abnormal leukorrhea and other symptoms, usually need to take 3 days to 5 days effective relief. 2. moderate infection: may cause urethral pain, urinary frequency, urinary urgency and lumbago symptoms, generally need to take 7 days to 10 days to effectively relieve. 3. Severe infection: may cause prostatitis, pyelonephritis and affect fertility, this situation can not rely on medication alone to relieve, need to be treated by infusion, generally preferred azithromycin, but azithromycin is easy to stimulate the gastric mucosa, you need to take omeprazole to protect the gastric mucosa. The common adverse reactions of Roxithromycin include nausea, vomiting, diarrhea, and abdominal pain, etc. It is contraindicated during lactation as well as in women during pregnancy. In addition, the application of Roxithromycin carries certain risks, and patients are advised to use the drug under the guidance of a specialist.