Positive IgG to Mycoplasma pneumoniae suggests a previous infection and production of antibodies in the body, while positive IgM suggests the presence of a current infection in the body and the need for active treatment. Mycoplasma pneumoniae antibody results include both IgG and IgM antibodies, and the normal reference value for mycoplasma antibody is within 1:32. If the IgM antibody result is greater than this range, and there are obvious symptoms of mycoplasma infection such as cough and fever, as well as imaging tests to support the diagnosis of mycoplasma infection, then it suggests that there is an infection in the body, and symptomatic treatment for the pathogen is needed. If the IgG antibody is only positive, it suggests that the body may have been infected with mycoplasma in the past period of time, and the body’s immune system has produced antibodies against mycoplasma, and despite the fact that the disease has already been cured, there are still antibodies in the body, which is why the IgG antibody shows a positive result. Therefore, positive IgG antibody cannot be used as the basis for diagnosing mycoplasma infection, while positive IgM antibody is an important indicator of acute mycoplasma infection.