Because, the total energy is not enough patients will be hungry, and the lack of protein total energy can only be fat or sugar overload. And no matter what kind of fat, the excess is frequently flowing in the blood vessels; whether or not there is sweetened sugar (starch breakdown is also sugar), the excess is no different from direct fat intake, and all of them are saturated fatty acids. Because, fat is not consumed energy in the body almost the only way to store and compensate, and storage must be processed into a low-density saturated state before. Therefore, fat restriction at the expense of quality protein restriction will not only not work, but will be more harmful. The reason for this is that most patients do not understand the interactions and transitions between nutrients and have difficulty learning about them. However, the problems they cause are very serious. The interrelationship between protein, fat and sugar is described as follows: First, energy is the power that ensures that the basic vital activities of the body, such as respiration, heartbeat and other basic metabolism, exercise and digestion, cannot be interrupted. The main substances that the human body can use for yield are proteins, fats and sugars. Since the natural form of sugar is very complex, it also uses its characteristics after metabolism, namely: all produce carbon dioxide and water, and are called carbohydrates. However, since these nutrients also have their own functions, where the main task of protein is to synthesize and repair human tissues, immune substances, etc. Fats and carbohydrates, although they also have a very important significance and value in this respect, are used in smaller amounts, mainly to provide energy. At the same time, there are very complex interrelationships due to different metabolic characteristics, which produce different effects on each other. For example, without the help of adequate sugar catabolites, fats cannot be fully oxidized, thus very easily leading to ketoacidosis. Also, the influence and conversion process between nutrients is the cause of many important diseases such as diabetes and hyperlipidemia. For example, cardiovascular disease is not only seen in diabetes. Because, its underlying pathology: abnormal fat metabolism, which can be caused both by unreasonable dietary intake and by impaired glucose metabolism with wrong application of hypoglycemic drugs. Because (1) excessive protein or sugar intake, the body automatically converts it into fat. The reason is that the human body has very limited capacity of free amino acid pool (one of the forms of protein substitution and storage) and glycogen (direct storage form of sugar), while fat is almost the only storage and substitution method of the human body after energy generation; (2) insufficient capacity of sugar (hyperglycemia, high urine sugar, too little dietary sugar, wrong application of α-glucosidase inhibitors, biguanide hypoglycemic drugs, etc.) the human body will automatically burn protein and fat instead. Because, breathing, heartbeat and other basic metabolism of human body and exercise, digestion and other basic life activities of human body need energy can not be interrupted; (3) too much fat intake, more will directly raise the blood lipids. And because fat is stored under the skin and between the tissue organs, while its metabolism is in the liver. Therefore, although not all of these processes necessarily lead to dyslipidemia, too much fat running in the blood can lead to rapid hardening of blood vessels and eventually to cardiovascular disease. Not only that, but in fact other complications of diabetes are the same. For example, wounds that do not grow and infections that do not heal are also caused by a lack of raw materials for tissue repair and synthesis of immune substances due to insufficient sugar production and excessive protein consumption. Since protein cannot be synthesized in the body to meet its needs, it can only be consumed from the diet. Therefore, control of dietary energy and its composition is very important for health or disease prevention and cannot be solved by simply eating less or more of something. Because a medical field of study is only a “small account”, while nutrition is both a “small account” and a “big account”. Otherwise, it will only change from one kind of harm to another. The basic concepts, interrelationships and conversion pathways of protein, fat and sugar, as well as the basic concepts, interrelationships and treatment pathways of the five drivers of diabetes, are attached.