Most patients with septic thrombosis initially have a febrile response due to infection, with the following diagnostic indicators: sepsis Evidence of pathogenic microbial infection with two or more of the following: temperature >38 degrees or <36 degrees; heart rate >90 beats/min; respiration >20 breaths/min or partial pressure of CO2 <4.3 kPa (32 mmHg); white blood cell count >12×109/L or <4× 109/L or immature neutrophils >10%. Severe sepsis Symptoms of sepsis with the following manifestations: organ dysfunction; hypotension (arterial systolic blood pressure <90 mmHg, drop in blood pressure >40 mmHg); systemic hypoperfusion (lactic acidosis, oliguria, central nervous symptoms, other organ symptoms). Infectious (septic) shock with symptoms of sepsis, severe sepsis, and the following manifestations: hypotension and ineffective fluids; hypoperfusion (as in severe sepsis); hypoperfusion; systolic blood pressure <90 mm Hg or >40 mm Hg relative to basal pressure, excluding other factors causing hypoperfusion.