The prevalence of condyloma acuminatum 1, the prevalent population: the disease is more likely to sexually active young and middle-aged people, 20 to 40 years old, the incubation period is generally 1 to 8 months, the average of 3 months. The research found that this population is usually characterized by a low level of education and a certain mobility, such as migrant workers. Because they are young patients, they have limited financial affordability. However, there is no shortage of patients with a high level of education and better financial means. Clinicians respond that there are more men among patients, and if they are young and unemployed, they are usually “sex workers”, and women over 35 are usually infected by their sexual partners. 2, mode of transmission: sexual contact is the main route of transmission, HPV can be inoculated to the site through minor damage to the skin mucosa, after a certain incubation period, symptoms appear, the strongest infectious 3 months after infection. The non-sexual route of transmission includes the following: (1) contact with objects infected: healthy people may be infected through contact with towels, underwear, commode and other household items used by patients with condyloma acuminata or HPV infection. (2) Medical source of infection: including the medical personnel themselves are infected and the medical personnel to the patient’s infection, such as when the patient with condyloma acuminata or HPV infection is examined, laser, freezing, surgery or injection treatment without the necessary safety measures, the medical personnel themselves are infected. The same is true for medical staff who are examining or treating healthy people or non-condyloma patients, as the operation is not strict enough to use HPV contaminated equipment for healthy people or non-condyloma patients to cause condyloma or HPV infection (3) mother-to-child transmission: the following three ways: during childbirth, in utero infection and after the birth of the baby and the mother close contact transmission. Among these three ways, most scholars believe that the transmission is at the time of delivery, that is, the baby during the birth process through the birth canal infected by HPV or warts. (4) Smoke transmission: The presence of intact HPV DNA can be detected in the smoke of laser treatment of condyloma acuminatum. This result indicates that the virus is released into the air from the tissue during the vaporization of laser treatment of condyloma acuminatum, as well as HPV contamination of the nasal cavity, nasolabial folds and mucous membranes of the eyes and face of the patient after treatment. (5) autoinoculation transmission: in the clinic found suffering from external genital or anal condyloma acuminata patients, because their hands often contact condyloma acuminata in the hands or other parts of the body skin mucosa and cause condyloma acuminata. Epidemiology: The incidence of STDs, according to the 2001 national STD epidemic report, a total of 859,040 cases of eight STDs were reported in 31 provinces in China in the previous year, an increase of 2,59% year-on-year, and statistics from 2000 onwards are not yet available. In the 2005 WHO report on this subject, it was estimated that the actual number of new cases per year in China was 16 to 20 million; among them, the number of new cases of acromegaly was expected to be 3 to 6 million per year. Some unofficial information shows that the number of warts in China accounts for 20-31% of all STD patients, the 2nd or 3rd most common in the south of China than in the north. Due to the lack of effective culture and serological techniques for population screening, clinical observation is still the basic research method for the epidemiology of HPV infection. Also, due to the presence of a large number of asymptomatic subclinical and latent states, it is estimated that its incidence will take the first place.