Recently, we have encountered many children with Mycoplasma pneumoniae infection, and it is possible that there is a small epidemic of mycoplasma infection again this year. Mycoplasma pneumoniae lung infections are characterized by paroxysmal coughing, long duration of illness, and easy recurrence, and can have extrapulmonary damage, so it must be taken seriously by parents. Mycoplasma pneumoniae can easily infect individuals with allergies, and it can cause allergies itself, so many extra-pulmonary manifestations can be related to allergies, and because of the long duration of the disease, it can be easily confused with some chronic coughs. One of the major headaches for parents nowadays is their children’s chronic cough, which has been treated in many hospitals without success. In fact, I believe that it is important to be in contact with a relatively regular doctor for a long time, so that the doctor can gradually understand the overall picture and characteristics of the child’s condition, and through the response to treatment, speculate on the cause of the disease. When a child is sick, parents are very anxious, in fact, doctors are also very anxious, every responsible doctor wants their patients to be cured as soon as possible, so parents and doctors must understand each other and trust each other, the most important experience of my decades of practice is to fully communicate with parents, not only in the consultation room, but more importantly, after the follow-up visit, which is also a kind of “after-sales service This is a kind of “after-sales service”, right? This is very common in foreign countries, the domestic do less, we must work hard. Mycoplasma infection is an old topic, every year I have to mention, I hope parents can be vigilant.