It is often seen that patients come to the doctor with positive reports of HPV from blood tests, some even from large hospitals, but there are no warts lesions on clinical physical examination, and these patients are crowned with latent infections by our doctors, and even heavy use of antiviral agents, so it is necessary to clarify the relevant concepts. HPV is an epidermophilic virus that infects humans mainly through direct or indirect contact with contaminated objects or sexual transmission. After the virus invades the body, it stays in the skin and mucous membranes at the site of infection and does not produce viremia. Within 1 to 2 months of the appearance of the infected lesion, the corresponding antibody is produced in the blood against the infected virus, and at this time, if a blood test is drawn, the result will be positive and the positive rate is about 50-90%. However, this positive result is only antibody positive, not virus positive. HPV is divided into more than 200 types and can cause more than 10 kinds of diseases, such as flat warts, common warts, condyloma acuminata and other conditions. An average person with a wart will probably have a positive blood test for HPV. However, a positive result does not mean that the person has an STD or condyloma. This is why a blood test cannot verify whether or not you have a wart, and there is no need for treatment.