Acute myeloid leukemia m1 chances of cure vary according to the patient’s disease progression, clinical five-year disease-free survival as the definition of cure, the general cure rate is about 30%. Acute myeloid leukemia m1 bone marrow morphology will appear more progranulocytes, single morphology, the proportion of cytosolic and cytoplasmic nuclei is higher, the clinic is currently mainly based on chemotherapy, drugs including Zoerythromycin, cytarabine, etc. If acute myeloid leukemia m1 is evaluated by the prognostic evaluation of patients with high-risk, the cure rate is very low, and the survival of serious cases is only a few months. Prognostic high-risk is evaluated in patients with combined FLT3, RUNX1, ASXL, and TP53 gene mutations. The main clinical manifestations of acute myeloid leukemia m1 include anemia, fever, hemorrhage, and proliferative infiltration of leukemia cells, and in severe cases, it may also be combined with infections in several areas, especially stomatitis and pneumonia. If the diagnosis has been confirmed through examination, it is necessary to go to the hematology department of the hospital in time and standardize the treatment under the guidance of the doctor.