Waking up in the morning with swollen eyes also depends on whether it is edema of the eyes or redness of the eyes. If the eyes are simply edematous and there is no redness on the surface of the skin, and there is no obvious pain or signs of increased fluid in the eyes, it is likely that you did not rest well during the night, or that there was a metabolic problem caused by alcohol or allergies the day before. At this time, you should go to the hospital to rule out internal medicine, such as kidney or liver problems. If these problems are ruled out, it may just be an allergy or a transient metabolic problem, which can usually be resolved with rest or anti-allergy medication. If the redness of the eyelids, including the redness of the eyes with pain and increased eye discharge, is likely to be caused by a bacterial infection, local anti-inflammatory treatment with levofloxacin drops or tobramycin drops, and oral antibiotics, such as cephalosporin or amoxicillin, can be used as an adjunct.