HPV16 positivity, usually after three months to six months, there is about 20% chance of self healing. But found HPV16 positive to carry out a cervical biopsy, cervical multi-point biopsy, if the transformation area of type III, but also for the cervical tube scraping, to rule out pre-cancerous lesions of the cervix, if there is no abnormality can be given to the observation for the time being. However, HPV16 positive belongs to the high-risk of the high-risk, in general, women have to strengthen their own resistance, can be given antiviral drugs vaginal drugs or oral drugs to promote the strengthening of resistance, can be conducive to the HPV16 positive to negative, because HPV16 carcinogenicity is relatively high, or actively give the intervention of the treatment is better.