Chinese herbal medicine has been credited with the diagnosis and treatment of diseases, but in fact the blind use of herbal medicine can also lead to aggravation of the disease and even the occurrence of herbal nephropathy, leading to chronic renal failure and accelerated development of uremia in patients with kidney disease. With the development of science and technology, it is gradually recognized that there are many herbal medicines that can cause damage to the kidneys themselves: for example, it has been recognized that the herbal medicines Guanmutong, Guangfangfen, Aristolochia and Qingmu Xiang cause aristolochic acid nephropathy. Some are also toxic to the kidney straight, anti-rheumatic herbs, tianxian vine, aconite, etc. There are also some some herbs rich in potassium, kidney disease occurs after the kidney failure of potassium excretion disorder, oral intake of these herbs will lead to further increase in blood potassium, inhibit myocardial contraction and death. Patients with kidney disease are advised to take Chinese medicine under the guidance of a professional physician, and not to blindly listen to folk remedies and prescriptions.