Pre-conception health care: (1) Pre-conception health education and medical consultation: (1) Health education: comprehensive and detailed “pre-conception school” free courses to guide you how to grasp the best time to conceive, a reasonable balance of pre-conception nutrition and dietary structure, learn to adjust the pre-conception physiological and psychological conditions, informed choice of appropriate contraceptive methods, to avoid the impact of adverse environmental factors and other eugenic health care knowledge. We will also provide you with health care knowledge on eugenics, such as avoiding the influence of adverse environmental factors. 2.Medical consultation: Warm and private preconception health care consultation clinic, warmly receive both couples, according to each couple’s different situation, provide personalized advice and health care program. Properly guide couples preparing for pregnancy to voluntarily choose reasonable preconception medical examination items on the basis of informed choice. (2) Pre-conception health care medical examination: 1. General information: Detailed personalized consultation and pre-conception psychological condition assessment for pre-conception health care subjects’ work environment, living habits, past and present disease history, family and genetic disease history, and fertility history, etc. On the basis of inquiry and preaching, targeted laboratory testing items are recommended. 2.Pre-conception physical examination: meticulous physical examination, including professional gynecological and male examination of the reproductive system of both men and women, can screen out unknown but potential diseases or physiological factors affecting pregnancy and childbirth in pre-conception health care subjects. 3.Auxiliary project examination: The factors affecting eugenics and birth defects are very complicated, and the health foundation and living environment of each individual are different, so it is the most reasonable program to select targeted projects for testing on the basis of medical consultation. (1) Free special eugenics tests: TORCH test, reproductive tract infectious disease test (syphilis screening, HIV test, white belt routine), routine blood test, routine urine test, hepatitis B surface antigen, liver function and semen analysis. (2) Customized special tests: mycoplasma culture, chlamydia, blood grouping, anti-ABO antibody, vaginal ultrasound, reproduction-related hormone measurement, karyotype analysis, etc. (3) Comprehensive assessment of health status and health guidance: 1. Conduct a comprehensive assessment of the health status of preconception health care recipients based on general information and the results of preconception medical examinations. Provide medical advice on the existence of health problems that may affect fertility. 2.Following the principle of combining universal guidance and personalized guidance, provide guidance to couples planning to become pregnant before pregnancy, early pregnancy and prevention of birth defects, etc. 3, Combining risk assessment and guidance, detailing the clinical significance of the screening results and other potential risks leading to birth defects that still exist.