Acute T-lymphocytic leukemia is a type of acute lymphoblastic leukemia, which belongs to the more malignant types of leukemia. The treatment of acute T-lymphocytic leukemia is clinically divided into three phases: induction remission therapy, consolidation therapy, and maintenance therapy. In general, the common chemotherapy regimens used for induction of remission include VDLP regimens, which include vincristine, cyclophosphamide, roxithromycin, glucocorticoids, and levomucoidase. After induction remission, consolidation therapy is administered, and high-dose methotrexate and other drugs are commonly used for consolidation therapy. Common chemotherapeutic agents used for maintenance therapy include oral methotrexate and 6-mercaptopurine. In addition, for acute T-lymphocytic leukemia, lumbar puncture with intrathecal injection is also routinely done to prevent central nervous system leukemia. Of course, if a suitable bone marrow donor is available, hematopoietic stem cell transplantation therapy is preferable.