Most of the kidney diseases are a group of immune diseases, long-term proteinuria and the treatment of immunosuppressants make kidney patients with low immune function and weakened ability to resist external evil. Although chronic kidney disease patients are the most contraindicated to suffer from colds, they turn out to be the most susceptible to colds. The effect of cold on kidney disease The effect of cold or other chronic infections on the organism secondary to kidney disease patients are as follows. 1, triggering the recurrence of kidney disease After the infection of the body with the cold virus, the body produces antibodies that combine to form immune complexes. This can eliminate foreign antigens (bacteria or viruses), but the immune complexes formed will also be deposited into the kidney tissue, leading to inflammatory cell infiltration, inducing an inflammatory response, thus causing nephritis. That is why patients with kidney disease often experience episodes of carnal hematuria and an increase in proteinuria after a cold. 2, aggravate the disease During the cold, the body’s metabolism is hyperactive, metabolic products and a large number of harmful inflammatory mediators increase, these substances not only increase the excretory load of the kidney, but also may stimulate the local inflammatory response, accelerating the progress of kidney tissue lesions. Many patients not only aggravate proteinuria after the cold, but also deterioration of kidney function. 3, combined with drug renal damage There are many people in the cold regardless of its cause, first take antibiotics and then hang water, tossing themselves, the result of the cold is not well controlled but also caused a rapid deterioration of kidney function. In fact, most colds are caused by viruses and have nothing to do with antibiotic treatment. Many antibiotic drugs need to be excreted by the kidneys, and it is possible to induce kidney damage in the process of using the drugs. Even drugs that have been used in the past and are considered safe may cause kidney damage in fever and dehydration. Therefore, do not abuse antibiotics and other drugs that may harm the kidneys, especially intravenous infusions, without clear indications for their use.