The side effects of interferon in hepatitis B are more common: 1, myelosuppressive effect, the use of interferon in the first few weeks of the most obvious inhibitory effect on the bone marrow, there will be a decline in white blood cells and platelets; 2, transient flu-like symptoms, especially in the first and second injection will appear headache, fever, joint pain and other flu-like performance; 3, some patients will appear after the use of liver function The risk of inducing autoimmune disorders, some may induce hyperthyroidism or autoimmune hepatitis, etc.; 5, interferon has the risk of causing cardiac arrhythmia, the most common is the pathological sinus node syndrome; 6, long-term users have a very small number of depression or schizophrenia; 7, in the use of the process of hair loss, weight loss, fatigue and other phenomena.