Azoospermia can be divided into obstructive azoospermia and non-obstructive azoospermia. For patients with obstructive azoospermia, sperm can be obtained through testicular aspiration and then IVF can be performed; for patients with non-obstructive azoospermia, microscopic sperm retrieval can be performed to decide whether to use one’s own sperm for IVF or donor sperm for fertility. Our hospital has many unique advantages in assisting pregnancy in patients with azoospermia because of its mature IVF technology of the first, second and third generations, mature microsperm freezing technology and sufficient sperm donor.
The following assisted conception program is shared for the reference of azoospermic couples.
Description.
1. Option 1.
1) Suitable for: special groups of people, such as patients with paraplegia, coma, and inconvenient mobility; patients with sperm in testicular penetration outside the hospital, etc.
2) The advantage is that only one surgical sperm retrieval is required on the day of egg retrieval by the woman, reducing the number of sperm retrieval procedures; and the sperm that is united with the egg is freshly retrieved, reducing the need for artificial intervention of the sperm during freezing.
3) If the sperm cannot be retrieved at that time, the couple can immediately decide to use donor sperm for conception (only hospitals with sufficient sperm supply like ours can provide it), without delaying the treatment.
4) The prerequisite for choosing this option is that the couple must consider in advance that they are willing to use donor sperm for conception in the event that sperm cannot be obtained through surgery.
2. Option 2.
1) If sperm is available after puncture, it can be preserved by microsperm cryopreservation technology and can be thawed at the time of egg retrieval by the female partner without the need to retrieve sperm again at the time of egg retrieval (Note: in hospitals without microsperm cryopreservation technology, it is necessary to surgically retrieve sperm again on the day of egg retrieval).
2) If the female partner has more eggs and the male partner has less frozen sperm and poor morphology, another testicular puncture for sperm retrieval can be performed on the day of egg retrieval, to be informed in advance.
3. Option 3.
1) For patients with non-obstructive azoospermia, embrace, microscopic sperm retrieval and donor sperm for pregnancy can be chosen.
2) Depending on the condition of the female partner, donor insemination or donor in vitro fertilization can be used to help conception
4. Program IV.
1) Indications for microscopic sperm retrieval: sperm not retrieved by TESA; small testes (2-6ml); Crohn’s disease; cryptorchidism; Y chromosome c deletion; sperm not retrieved by TESA on the day of egg retrieval;
2) Advance preoperative preparation, hospitalization on the day of the woman’s overnight injection, surgery on the next day or the morning of the day of egg retrieval.
3) If sperm is available, IVF is done with own sperm. If you do not have sperm, you should decide to use donor sperm for IVF at that time.
4) If the sperm cannot be retrieved at that time, the couple can immediately decide to use donor sperm for IVF (our hospital provides the sperm source for this purpose) without delaying the treatment. The prerequisite for this option is that the couple must have considered in advance that they are willing to use donor sperm for IVF if sperm cannot be obtained surgically.
5) If the female partner does not agree to IVF, microscopic sperm retrieval can be done first, with sperm freezing; spermless sperm can be chosen for donor insemination, adoption, etc.