Anti-tuberculosis treatment is needed after lung tuberculosis ball surgery to prevent recurrence of tuberculosis. Lung tuberculosis ball is a special structure formed during the healing process of tuberculosis, there may be no tuberculosis bacilli inside, only the lesion forms a fibrous foci, even after the tuberculosis ball is removed through surgery, there may still be active tuberculosis bacilli in the lung. Therefore, after lung tuberculosis ball surgery, it is still necessary to adhere to the anti-tuberculosis treatment for about half a year to completely remove the tuberculosis bacilli from the lungs, to avoid the recurrence of tuberculosis bacilli and the reappearance of lung lesions. After the completion of pulmonary tuberculosis ball surgery, in addition to anti-tuberculosis treatment, should also be regularly re-examined lung CT, blood sedimentation, liver function and other indicators. According to the results of the review, the effect of the treatment as well as the adverse drug reactions should be evaluated, and the medication regimen should be adjusted in a timely manner under the guidance of the specialist.