The thyroid gland is the largest endocrine organ in the body and is located in the neck in front of the trachea and below the laryngeal nodes, mostly in the shape of a bipteryx. Because of its superficial location, it is easily visible or palpable when enlarged. When the thyroid gland becomes inflamed, it often causes neck pain, the majority of which is subacute thyroiditis, or subthyroiditis. The cause of subacute thyroiditis is related to a viral infection and most patients develop it after an upper respiratory tract infection. It is common in the spring and autumn, mostly in middle-aged women, and has an acute onset. It is characterized by pain in one or both lobes of the thyroid gland, which can be untouchable in severe cases, making it difficult to sleep and causing radiating pain in the back of the neck, behind the ears, and at the back of the head. Some patients also have fever, mostly low-grade, and may feel weak and have a decreased appetite. Some patients have a mild manifestation, with only discomfort in the throat. Recently, we have had many patients with neck pain in the thyroid clinic of our city hospital. Some of them were referred to our department after the ENT examination did not show any obvious abnormality and were diagnosed with subacromial nail infection. There are also many patients who come to our thyroid clinic with a diagnosis of subthyroiditis after various tests and anti-inflammatory treatments at the primary hospital have failed due to chronic low fever. Subarachnoiditis is an immune disease related to viral infection and is different from the popular understanding of bacterial inflammation, and simple antibiotic treatment is not effective. If you have neck pain please be alert to subxiphoiditis and go to a major regular hospital for examination and treatment to minimize your pain.