There are two types of anti-inflammatory drugs used for ankylosing spondylitis: i. Non-steroidal antipyretic and analgesic drugs, also called non-steroidal anti-inflammatory and analgesic drugs. Depending on the patient’s condition and gastrointestinal resistance, choose the following two kinds: 1. If the patient’s gastrointestinal tract functions well and there is no gastrointestinal discomfort from taking medication, such as bloating, nausea, vomiting, diarrhea, etc., you can choose non-selective COX-2 inhibitors, such as diclofenac. 2. If the patient’s gastrointestinal tract is not good and there are frequent gastrointestinal discomfort symptoms, such as nausea and vomiting, after taking medication Heartburn, acid vomiting, belching, indigestion, it is necessary to choose specific COX-2 inhibitors or use selective COX-2 inhibitors, such as etoricoxib class. These drugs have good anti-inflammatory and analgesic effects, small gastrointestinal adverse reactions, good patient tolerance, and can be used consistently, so they are now more clinically used drugs. Second, steroidal antipyretic and analgesic drugs, such as glucocorticoids, can be used to play joint cavity injection, but also the sacroiliac joint local acupuncture point injection use.