Hepatitis B surface antibody quantitatively greater than 1000 is not serious and can also be a good defense against the chances of invasion by the hepatitis B virus. Hepatitis B surface antibody is one of the tests in the hepatitis B two-half test. If surface antibody is produced through hepatitis B vaccination, or if surface antibody is produced by autoimmune elimination of the virus after an acute infection, it means that there is immunity to hepatitis B virus infection. Hepatitis B surface antibodies have the ability to neutralize viral particles, allowing the virus to break down and preventing the hepatitis B virus from becoming infected. The higher the value of hepatitis B surface antibody, the better the protection of the body against foreign invasion of hepatitis B virus. The two halves of the test should be reviewed regularly to avoid the antibody from becoming negative, which may increase the possibility of hepatitis B infection. Hepatitis B surface antibody quantitative 1000 is not serious, and also has the ability to protect the body against foreign invasion is relatively strong. As the antibody will gradually decrease or even turn negative, the quantitative two half of hepatitis B should be rechecked regularly, and the surface antibody titer should be replenished with hepatitis B vaccine in time when it decreases.