The first generation of IVF and the second generation of IVF have differences in terms of indications, specific operation and price, which need to be specifically analyzed. 1. Indications: the first generation of test tube function is relatively basic, in addition to the indications of the female factor, in the male aspect of the male oligozoospermia, as well as mild to moderate deformed spermatozoa, the second generation has developed on the basis of this, but also for the male severe deformed spermatozoa, obstructive azoospermia and so on. 2. Specific operation: the first generation of test tube is to put sperm and egg cells into the culture fluid to promote the formation of fertilized eggs, the second generation of test tube can artificially select high-quality sperm to be injected into the cytoplasm of the egg. 3. Price: The second generation of IVF is more expensive than the first generation due to the technological innovations that have occurred. If you need to undergo IVF, it is recommended that you visit a hospital in time and choose the right way for you under the guidance of your doctor in order to promote a successful pregnancy.