Lipids in blood plasma are collectively called blood lipids, which are the substances that supply energy to the body and are mainly composed of cholesterol and triglycerides, and cholesterol is divided into high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and very low-density lipoprotein cholesterol (VLDL-C). Among them, HDL can transport cholesterol out of the body and is called “protective cholesterol”. Most of the other lipid components are higher than normal and may cause a variety of clinical conditions. Clinically, lipids are often measured as the amount of lipoprotein-bound cholesterol or triglycerides in fasting (12 hours or more of fasting) plasma, including: total cholesterol (TC), HDL cholesterol, LDL cholesterol, triglycerides (TG), etc. 1.Harm of hyperlipidemia After years of clinical and basic medical research, it has been clearly confirmed that hyperlipidemia is the main risk factor causing atherosclerotic diseases in humans. Common atherosclerotic diseases include coronary heart disease (including myocardial infarction, angina pectoris and sudden death), cerebral infarction and peripheral vascular thromboembolic diseases. These cardiovascular and cerebrovascular diseases have a high incidence, great danger, the progress of the disease is dangerous, its death rate accounts for about half of the total human mortality, is the first killer of humans! 2, only fat people will have elevated blood lipids? There is a modern epidemiological study: hypertension, hyperlipidemia, coronary heart disease, diabetes, obesity, etc. collectively referred to as “affluenza”, that is to say, the occurrence of these diseases, in addition to a small number of genetic factors, biological factors, mainly with the improvement of living standards, changes in lifestyle habits, intake and consumption balance imbalance, lack of exercise and other factors closely related. Lack of sports and exercise are closely related to such factors, that is, the negative effects caused by improved living conditions. However, 2/3 of human serum cholesterol is produced by the body itself, and only 1/3 is obtained by diet. Therefore, hyperlipidemia is not entirely a result of eating, and its causes are complex. It can be secondary to kidney disease, diabetes, severe liver disease, etc., or it can be due to family genetic reasons. 3, the common causes of hyperlipidemia: (1) high cholesterol: excessive intake of saturated (animal) fat in the diet, cirrhosis of the liver, poorly controlled diabetes, low A, kidney disease and hereditary hypercholesterolemia. (2) High triglycerides: excessive caloric intake, alcohol abuse, uncontrolled severe diabetes, kidney disease, certain drugs (e.g. estrogen, etc.) and hereditary hypertriglyceridemia. Hyperlipidemia can be clinically classified as primary or secondary according to its etiology. The latter is caused by other diseases and has a lower prevalence. Primary hyperlipidemia may be associated with abnormalities in genes, lipoproteins and their receptors or enzymes. However, hyperlipidemia is also associated with many other risk factors for atherosclerosis. 4. Criteria for lipid control Lipid control is different from other clinical indicators, and different target populations have different lipid control requirements. Clinicians need to personalize treatment according to the characteristics of different populations.