As we know, the prevalence of kidney disease in the population is around ten percent worldwide, and China is no exception. In other words, one out of every ten people may be a kidney disease patient. The vast majority of them are what we often call nephritis, but is nephritis really as terrible as you think? We know that the kidney is an important organ in the human body, it mainly eliminates toxins, maintains the electrolyte balance in the body, maintains the water balance in the body, and secretes some hormones, such as renin and erythropoietin, the former regulates our blood pressure, the latter maintains the hematopoietic function of the body. Therefore, the kidney is a very important organ of the human body. If there is a problem with the kidney, it may manifest as proteinuria, hematuria, and elevated creatinine. Patients may feel the symptoms themselves: swelling, poor circulation, weakness and pallor. So will these patients with nephritis definitely lead to uremia? If you have uremia, is it as terrible as you think? I think this is a question that we all care about. First of all, let’s talk about the knowledge of nephritis. Nephrolithiasis is a very broad concept, the types of nephritis and lesions that will really cause uremia are relatively few, we know that there are nearly 100 million nephritis patients in China a year, but those who cause uremia are only 200,000 to 300,000 patients, most nephritis patients will not cause uremia, they may be accompanied by abnormal urine tests or minor manifestations throughout their lives, but it does not lead to uremia, therefore Not all patients with nephritis will enter uremia. From clinical experience, patients with simple mild hematuria tend to have a better prognosis. Only a very small number of these patients enter uremia; if clinical tests suggest a small amount of hematuria combined with proteinuria, these patients can often take drugs to effectively control the disease and prevent him from entering uremia. Only those patients with stubbornly large amounts of proteinuria or proteinuria with hematuria are often prone to uremia, and these patients need timely and effective treatment. In our country, the current diagnosis and treatment of nephritis are diverse, and many in primary hospitals and units do not have the means to perform kidney biopsy, nor can they figure out the type of nephritis etiology and its true causative factors. Therefore, most of the treatments for nephritis are some empirical treatments. These empirical treatments may lack targeting and may cause some side effects to achieve the effect of controlling the disease, such treatment method may bring some harm to our nephritis treatment, therefore, this will be our difficult point. The kidney biopsy technique is not carried out in every unit, especially at the level of county hospitals in China, few units can carry out kidney biopsy, so the treatment for these patients is often chosen not necessarily the best treatment strategy. And non-optimal strategies and protocols may increase the chances of progression of nephritis to end-stage renal disease. In the treatment of nephritis, many people have a misconception that nephritis may be cured, and they always go around the country looking for medicine, eventually trying to find a panacea to cure nephritis, but the fact is that in all kinds of nephritis, except for acute post-infectious glomerulonephritis, which can be cured, the vast majority of patients with nephritis need a lifetime of medication and are difficult to cure. Therefore, bringing the disease under control and maintaining stable kidney function and avoiding deterioration of kidney function is the main task of our kidney treatment and the main means of nephritis treatment, not to cure this nephritis. This is the point that we need to recognize. Kidney disease in the process of development, always will gradually develop in a bad direction, the main purpose of our treatment is to slow down the speed or so that this lesion does not progress, thus extending the time frame to enter uremia. Imagine. If you have not entered uremia at the time of your death, then the kidney is not the main cause of death and will not affect your life expectancy. Therefore, we must establish the idea that the treatment of nephritis is a lifelong, long-term process, and few people can cure nephritis completely. Therefore, most of the patients with nephritis can continue his work, continue his career, family during the treatment process without much impact. But unfortunately many patients with nephritis, even if the disease is very mild, but due to the great ideological pressure, that they may enter uremia, will lead to kidney failure, thus causing a heavy burden on their minds, this ideological burden, far greater than the pain caused by the disease itself, so we need to point out that these patients, even if you have nephritis, if it is very mild nephritis, you can ignore It is to completely let go of the mind. But it does not mean that you do not see the doctor, you still need to follow the doctor’s advice for regular review and regular follow-up. The actual fact is that you should not be overburdened in your mind so that you can get an optimal result. What we just talked about is nephritis. Some patients with nephritis are difficult to control after treatment and finally enter uremia. So even if you get to uremia, is it a very scary situation as we all think, a hopeless stage? Actually, it is not. With the development of nephrology technology, since the 1960s when dialysis and kidney transplantation could be carried out, the uremia we are facing is not terrible. As we know, if you have cancer, or other incurable diseases, the consequences are very serious because it will be life-threatening. However, having a UTI, thanks to these modern advanced technologies, can enable a person to delay their life span and enable them to continue living a quality life. There are three options available to a person who has a UTI: the first is hemodialysis, the second is peritoneal dialysis, and the third is a kidney transplant. Nowadays, both hemodialysis and peritoneal dialysis technologies are relatively mature, so whether you are in the city or in the countryside, whether you are near a hospital or in the countryside, we can find some effective alternative treatment methods. Among these three options, kidney transplantation is the best, many people can start a new life after successful kidney transplantation, return to work, start their career again, enjoy their life again, many people can get married and have children after kidney transplantation, can do what they want to do. We know that in the United States there is an NBA star, Mourning, who returned to the NBA game after a kidney transplant. In Europe, the German team Werder Bremen has a Croatian striker, Krasniqi, who was able to play and score in the World Cup after a kidney transplant, which tells us. Even if we have UTI, we should not be pessimistic, there is still a way for us to get a successful life again. We can start our own more normal life and create our own career. Therefore, our kidney disease even to the worst stage of uremia, there are still ways. Many people worry every day during the treatment process, bringing some fear, bringing pressure on the mind including the pressure on the family. So here is what needs to be pointed out to you to relieve stress. Most of the nephritis will not lead to uremia, even if part of it to uremia, we still have a way. We know that the success rate of kidney transplantation in China is basically over 95 percent, and the survival rate is increasing significantly one year, three years, five years and ten years after surgery, and we will have more and more patients with more than twenty or thirty years. There are also kidney transplants even if the first failed, but also the second transplant, the third transplant, these are to give us a lot of hope, therefore, we can not despair even to uremia, we still need to actively face these problems, this is the characteristics of our kidney disease. We should not turn the anxiety about our disease into a heavy burden. If you have the opportunity to communicate with patients after kidney transplantation, you can have a better understanding of your disease. Of course, if a person has chronic nephritis and uremia, what he needs to pay attention to and his own lifestyle will change with his disease, especially in the degree of exertion, diet control, and some occupational choices, there will be requirements, I think in this process, our doctors will give you some guidance, I think as long as the patient and the doctor have a good communication, then, I believe that even nephritis patients and uremic patients have hope and reason to get a new life.