Wrinkle reduction injections are a commonly used technique for micropigmentation. Commonly used injections include Botulinum toxin type A and Hyaluronic acid. Wrinkle reduction injections are not a one-shot fix, one injection can last for 6-8 months, and another injection is needed after six months. The hazards of wrinkle removal injections are small, but if the operator lacks professional knowledge and operates improperly, it may lead to some hazards. 1, local muscle dysfunction, for example, when injecting the forehead muscle, if the position is too low or the amount of injection is too much, it will lead to difficulties in raising the eyebrows, if the upper eyelid lift muscle is paralyzed, it will lead to difficulties in opening the eyes, but these conditions will gradually recover with the absorption of the injected agent; 2, if hyaluronic acid injection is applied to remove wrinkles, nodules will be formed when the injection is too shallow, if it enters the blood vessels, it will lead to vascular embolism, and in serious cases, it will lead to skin necrosis 3. If botulinum toxin injection is applied to remove wrinkles, it will cause botulinum toxin poisoning when it exceeds the normal use amount, and it will cause more obvious harm when the injection site is wrong, such as stiff facial expression, asymmetry, or the whole face is not coordinated. Therefore, it is recommended that candidates should choose regular hospitals and qualified doctors for wrinkle removal injections to minimize the risk and ensure the surgical effect.