Pulmonary sarcoidosis is a cell mass formed by fibroblasts together with inflammatory cells, mainly due to abnormal autoimmune function or various microbial infections. Pulmonary granuloma mainly occurs in tuberculosis. It is recommended to visit a hospital promptly to check the chest CT and give tuberculin test examination if necessary. In case of pulmonary tuberculosis granuloma, anti-tuberculosis medication, such as isoniazid, rifampin and other drugs, is needed at this time, and constant attention should be paid to observe the condition of the body. If the effect of medication is not obvious, surgical excision can be used for treatment. Routine pathological examination is performed after surgery to see what the nature of the granuloma is. It is mainly postoperative pathology that can clarify the nature of the granuloma.