Why is TCT + HPV testing the best screening option? Why is it the best option? This is determined by the characteristics of both methods. Because TCT has a higher specificity but slightly lower sensitivity, while HPV testing has a high positive rate but lower specificity, the combination of the two can complement each other and increase the positive detection rate. The positive detection rate of TCT, according to the literature, is 80% in the world’s leading research centers, examined by leading cytopathologists, while in the domestic tertiary hospitals, this positive detection rate is difficult to compare, high-level laboratories may reach 50% or higher, then the low-level laboratories, even the newly introduced equipment, the results of the test can be imagined ( I am sitting in the The last thing I want to see when I sit in the clinic is a patient holding a TCT report form from a certain medical examination center and asking me what to do with it. Because I really don’t know what its positive detection rate is and how to deal with it). If we add HPV testing, its test efficacy will be completely different.