Condyloma acuminatum, an epidermodysplasia verruciformis growth in the genital, perineal, and anal areas caused by human papilloma virus infection. It is the most common sexually transmitted disease worldwide. Recurrent attacks are one of the characteristics of the disease, especially urethral warts are difficult to treat. In the past, ordinary laser treatment was generally used, but the treatment was painful for the patient and the recovery after treatment was slow, and it was easy to produce urethral scarring that led to stricture. 5-Aminoketovaleric acid photodynamic therapy, referred to as Ira photodynamic therapy, is a joint application of photosensitizers and the corresponding light source, through the photodynamic response to selectively destroy the lesion tissue of a new technology. It has the characteristics of high cure rate, low recurrence rate and good safety. It is especially suitable for the treatment of male urethral warts. The characteristics of this technology: 1. Good selectivity. 2, small trauma. As the treatment is highly selective, can avoid and significantly reduce the surgery and other laser treatment caused by trauma and pain, and no ulcers and scars formed. 3.Less pain. No obvious pain during treatment. 4.It can eliminate the hidden lesions, and the recurrence rate is low. 5. Repeatable treatment, lesion cells will not be resistant to photosensitive drugs. Treatment process: Dressing Ira 3 hours → 635nm PDT laser treatment instrument local irradiation 20min.