You can’t judge whether the patient’s condition is serious only from the high complement C1q, but have to make a comprehensive analysis from the causes of the high complement C1q, the specific condition and the patient’s personal physique and so on. High complement C1q is mostly seen in autoimmune diseases, malignant tumors and various infectious diseases. Complement C1q is a kind of glycoprotein produced by mast cells, macrophages and other cells, which has the function of adjusting immune cells and maintaining immune tolerance of the body, and there is some clinical significance in the elevation or decrease of the test value of complement C1q, which is mainly seen in autoimmune diseases such as systemic lupus erythematosus, polymyositis and other autoimmune diseases. In addition, elevated C1q values can also be seen in malignant tumors such as osteosarcoma, multiple myeloma, and infectious diseases such as pneumonia and infective endocarditis. Complement C1q test value higher than the upper limit of the reference range is abnormal, but only from the complement C1q is high can not judge whether the patient’s condition is serious, the specific severity of the condition according to whether the underlying diseases, age and whether the diagnosis of autoimmune diseases, malignant tumors and other related factors patient’s specific condition may also have a greater difference. Laboratory test results should be interpreted by a professional physician, and it is recommended that patients go to the rheumatology and immunology departments of regular hospitals for detailed consultation and treatment in accordance with medical advice.