Once I met a woman in the clinic who had been suffering from chronic urticaria for more than a year and whose symptoms were completely controlled by taking antihistamines. This is a difficult question for me because studies have shown that the average duration of chronic urticaria is 2-5 years, which is the result of long-term observation and follow-up in a large number of people, but it is difficult for me to predict when a particular patient will be cured. This woman later revealed her innermost secret: she had been told that hives had an effect on pregnancy, so she had to wait until the hives cleared up before she got pregnant. There are many patients who are really confused about pregnancy and hives and medication. Does hives favor mothers-to-be? Chronic spontaneous urticaria is more common in women (twice as common in women as men) and changes in women’s hormone levels may affect the severity of urticaria symptoms, for example, some women with chronic urticaria experience a temporary increase in urticaria symptoms around their menstrual period. However, there is insufficient research data to prove that hives are more likely to occur during pregnancy, and some women with chronic hives experience an increase in symptoms during pregnancy, while others feel a decrease or even a decrease in symptoms. Can hives affect the development of the fetus? Urticaria itself does not adversely affect the development of the fetus, but it is important to note that if acute urticaria manifests itself during pregnancy along with systemic allergic reactions such as difficulty breathing and lowered blood pressure, the fetus may be at risk due to hypoxia or hypotension. Therefore, women who have had previous episodes of acute urticaria with systemic allergic symptoms must avoid contact with foods (most commonly seafood, shellfish or nuts), medications (most commonly penicillin and cephalosporin antibiotics) or hymenopterous insect bites (such as bee, wasp or ant bites) during pregnancy, and always carry an epinephrine auto-injector with them in case of emergency. For self-help. Can urticaria be passed on to children? Urticaria, especially chronic urticaria, occurs in people with allergies, and some urticaria sufferers have family members or relatives who have suffered from urticaria more often. However, chronic urticaria is a disease that is influenced by a variety of factors, and even though the mother-to-be may pass on a “hives-prone” constitution to her child, whether or not the child develops hives in the future is also related to the child’s living environment and lifestyle. So don’t worry too much about it. Can I take medicine if I get hives during pregnancy? For non-pregnant women, second-generation antihistamines are the drugs of choice for acute or chronic urticaria, and some antihistamines can still be used if you are pregnant. According to the classification of drugs in pregnancy, the second generation antihistamines, cetirizine (10 mg once a day, once a day), levocetirizine (5 mg once a day, once a day) and loratadine (10 mg once a day, once a day) are in category B. Each of these drugs has data from a large number of studies in pregnant patients to confirm their safety and can be considered as the antihistamine of choice in pregnancy. Chlorpheniramine (paracetamol), a first-generation antihistamine, has also been recommended as the first-generation antihistamine of choice during pregnancy, although it should be taken once every 4-6 hours at 4 mg, with the total daily dose not exceeding 24 mg. Therefore, if you develop unbearable itching hives during pregnancy, the mother-to-be does not need to tolerate it and can choose one of the above drugs The treatment can be carried out.