Long-term aspirin stomach upset can be improved by dietary adjustments, medication, changing medication or stopping medication. 1. Dietary adjustments: daily life should eat small meals, to light and easy to digest food, avoid overeating, can help relieve the upset stomach. 2. Medication: If you have an upset stomach after taking aspirin, but it is not serious, you can take acid-suppressing drugs such as omeprazole, lansoprazole, or gastric mucosal protectants such as colloidal bismuth as prescribed by your doctor. 3. Replacement of drugs or stop: If you take aspirin after the emergence of serious gastric discomfort need to be in the doctor’s guidance to stop aspirin treatment or replace the stomach irritation of similar drugs such as clopidogrel. Long-term aspirin stomach bad situation is recommended to go to the hospital, ask the doctor to judge, give professional advice.