There is a difference between HPV positive and Ureaplasma urealyticum positive. HPV positive is human papillomavirus positive, its infection mainly causes human epidermal and mucosal proliferative lesions, such as high-risk HPV (type 16, 18, etc.) can cause vaginal, cervical intraepithelial lesions, and cervical cancer and other malignant tumors related to the occurrence of low-risk HPV (type 6, 11, etc.) can cause genital warts and so on. Ureaplasma urealyticum positivity is mainly due to the presence of Ureaplasma urealyticum, which can cause vaginitis, cervicitis, pelvic inflammatory disease, non-gonococcal urethritis, etc. The relationship between Ureaplasma urealyticum positivity and the reproductive prognosis, such as preterm delivery, miscarriage and fetal developmental abnormality is not clear at present. Treatment is required if symptomatic UTI is diagnosed, other causes of pelvic inflammatory disease, etc. are ruled out. Whether HPV-positive or Ureaplasma urealyticum-positive, it is recommended that patients go to a regular hospital in a timely manner for consultation and standardized treatment under the guidance of a doctor after a definitive diagnosis is made, as well as undergoing treatment with their sexual partners and regular review.