The formation of high uric acid is caused by excessive urate production and/or decreased renal excretion of uric acid, or a combination of both. Purines are metabolites produced in human metabolism, and the end product of purine metabolism is uric acid. When there is a purine metabolism disorder in the human body that leads to overproduction of uric acid or impaired renal excretion of uric acid, the patient’s body blood uric acid level will appear to be elevated, and the elevation of uric acid can be divided into two categories: primary and secondary. Primary elevated uric acid is related to excessive production of uric acid caused by genetics and diet, related diseases are type I glycogen accumulation disease, familial juvenile hyperuricemic nephropathy, etc. Secondary factors include blood system diseases, drugs, kidney disease and lactic acidosis, excessive exercise, hunger, etc. It is recommended that patients with high uric acid should go to endocrinology and rheumatology departments of regular hospitals for detailed consultation and treatment according to doctor’s instructions.