In recent years, with the improvement of the standard of living, more and more female friends from adolescence to the age of childbearing, menstruation for the first time without any regularity, and even have no pregnancy. Some women not only have the name “little fat girl”, but also have skin covered with “acne”, no matter what expensive skin care products are used to no avail. Some women have excessive hair on their breasts, arms, thighs and midline areas of their bodies. Some women are misunderstood by others as “not paying much attention to cleanliness”, their neck, armpit skin and other parts of the skin is dark, as if not washed in the shower, especially embarrassing in public. If you have any of these problems, your first choice should not be to choose expensive skin care products, but to see a doctor. You may be suffering from polycystic ovary syndrome (PCOS). Polycystic ovary syndrome is the most common endocrine disorder in women of reproductive age, and its a metabolic disorder. Typical clinical manifestations are irregular menstruation, infertility, hirsutism and obesity. The disease can cause long-term complications such as diabetes mellitus, cardiovascular disease, endometrial hyperplasia, and even endometrial cancer. So is this disease a case of multiple cysts on the ovaries? The answer is no, this disease is due to the effects of mental stress, medication and certain diseases, causing the hypothalamus to lose its cyclical secretion of gonadotropin-releasing hormone, resulting in an imbalance in the ratio of gonadotropins secreted by the pituitary gland, causing the follicles to develop but not mature and not ovulate, becoming cystic follicles, and over time many cystic follicles are created, and finally the ovaries form grape-like polycystic ovaries, which can be seen on ultrasound. In this case, “polycystic ovarian changes” can be seen on the ultrasound. This is not a single disease, but rather a multi-causal and highly heterogeneous condition called “polycystic ovary syndrome”. What kind of tests do patients need? 1. Physical examination, the medical staff will measure height, weight, waist circumference, hip circumference, etc. and calculate body mass index to evaluate the condition in detail. 2.Endocrine examination will be performed from the first day of menstruation to about the 3rd day of menstruation. 3. Ultrasound examination will be performed after menstruation. 4.Checking related to metabolism, such as blood glucose, insulin and blood lipids, to predict the possibility of diabetes and other complications in the future. In polycystic ovary syndrome, we need to address not only the immediate problems such as irregular menstruation and seizures, but also the possible long-term complications caused by the disease: such as diabetes, cardiovascular disease, and even endometrial cancer. What treatment does the patient need to receive? First of all, for obese patients, it is important to increase exercise, eat properly and control weight. Medication can be administered to help patients establish regular menstrual cycles, as well as to improve symptoms such as hirsutism and acne. For patients with very high body hair, laser hair removal can be used; for patients with elevated blood sugar and insulin, we use medications to improve blood sugar; for those who are not pregnant, we use ovulation-promoting medications. Each patient suffering from polycystic ovary syndrome has different symptoms, different needs and different sensitivity to drugs, which requires individualized treatment, and its treatment is a long process that requires close communication and joint efforts between doctors and patients.