Newborns with poor grip response may be physiological reasons, but also may be the cause of disease, such as hypoxia, brachial plexus nerve injury, etc., the specific analysis is as follows: 1. Physiological factors: if the newborn appears above, and belongs to the preterm baby, it may be due to the primitive reflex is not fully formed, with the development of the newborn’s age, the brain gradually develops and matures, it will slowly appear after the grip response. 2. Pathological factors: if the newborn is born with cerebral hypoxia, it may also lead to the disappearance of the primitive reflexes; in addition, if it leads to brachial plexus nerve injury in the process of labor, the newborn may have the above situation. Newborns with poor grip response, there may be other reasons, parents are advised to go to the hospital in a timely manner for relevant examinations, clear causes and then actively treat the symptoms.