Mood (state of mind) stabilizers: drugs that have therapeutic and relapse prevention effects on manic or depressive episodes and do not cause manic and depressive transitions, (that is, depressed patients will not cause or induce manic episodes after taking them) and do not lead to frequent depressive and manic episodes. The main ones are: sodium valproate, lithium carbonate, carbamazepine, and also Toltea, lamotrigine, etc. Patients suffering from bipolar disorder should use mind stabilizers on a basic basis, no matter they are in manic episodes, such as: excitement, talking a lot, high mood, high energy, exaggerating, bragging, etc.; or in depressive states, such as: low mood, no spirit, little interest, feeling no fun, etc. As long as the previous clear diagnosis of ‘bipolar disorder’, or depressed patients with family history of bipolar disorder, or younger age of onset, they should take ‘mood stabilizers’, which can reduce the number of manic episodes or frequent episodes caused by taking only antidepressants, and also reduce interphase transitions between depression and mania. Some patients who do not use mood stabilizers will have frequent episodes, which will make treatment more difficult and affect the prognosis. In addition, in some refractory schizophrenia, when antipsychotic treatment alone is ineffective, mood stabilizers can also be used as a booster to improve the efficacy of antipsychotics.